Porphyrins urine test

定义

Porphyrins are natural chemicals in the body that help form many important substances in the body. One of these is hemoglobin, the protein in red 血 cells that carries oxygen in the 血.

Porphyrins can be measured in the urine or 血. This article discusses the urine test.

Alternative Names

Urine uroporphyrin; Urine coproporphyrin; Porphyria - uroporphyrin

How the Test is Performed

After you provide a urine sample, it is tested in the lab. This is called a random urine sample.

If needed, your health care provider may ask you to collect your urine at home over 24 hours. This is called a 24-hour urine sample. Your provider will tell you how to do this. Follow instructions exactly so that the results are accurate.

How to Prepare for the Test

Your provider may tell you to temporarily stop taking medicines that may affect the test results. These may include:

• Antibiotics and anti-fungal drugs
• Anti-anxiety drugs
• Birth control pills
• Diabetes medicines
• 疼痛的药物
• Sleep medicines

Do not stop taking any medicine without first talking to your provider.

How the Test will Feel

This test involves only normal urination and there is no discomfort.

Why the Test is Performed

Your provider will order this test if you have signs of 卟啉症 or other disorders that can cause abnormal urine porphyrins.

正常的结果

Normal results vary depending on the type of porphyrin tested. 在一般情况下, for a 24-hour urine test of total porphyrins, the range is about 20 to 120 µg/L (25 to 144 nmol/L).

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

Abnormal results may be due to:

• 肝癌
• 肝炎
• 铅中毒
• Porphyria (several types)

风险

There are no risks with this test.

参考文献

Fuller SJ, Wiley JS. Heme biosynthesis and its disorders: 卟啉症s and sideroblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8日艾德. Philadelphia, PA: Elsevier; 2023:chap 39.

转变RJ. 的卟啉症. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26日艾德. Philadelphia, PA: Elsevier; 2020:chap 199.

Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24日艾德. Philadelphia, PA: Elsevier; 2022:chap 29.